Reddit mentions of Moon Called (Mercy Thompson)

The Brief, Wondrous Life of Oscar Wao

..with the caveat that it's really only almost fantasy. It has the tone, and there's one or two fantasy type elements here and there, but it's a real-world setting. That said, I loved this book. It's one of my favorites.

>Oscar is a sweet but disastrously overweight ghetto nerd who—from the New Jersey home he shares with his old world mother and rebellious sister— dreams of becoming the Dominican J.R.R. Tolkien and, most of all, finding love. But Oscar may never get what he wants. Blame the fukú—a curse that has haunted Oscar’s family for generations, following them on their epic journey from Santo Domingo to the USA.

Ursula K. Le Guin is pretty reliable when it comes to mixing up PoCs into her books, so I'd search that. Bonus, she writes both science fiction and fantasy iirc so she might have something in between.

Isabel Allende -- she's technically a Latin American literary type author, but a lot of Latin American literature is uhhhh.... I think the term for it is "magical realism." They're typically set in South America, often the characters or themes relate to native populations, and I recall a secondary character in one book who was essentially a MtF transsexual.

Aha! I found it. It's Eva Luna.

>As the years pass and her imprudent nature sends Eva from household to household—from the home of a doctor famed for mummifying the dead to a colorful whorehouse and the care of a beautiful transsexual—it is Eva’s magical imagination that keeps her alive and fuels her ardent encounters with lovers of all kinds. And as her South American homeland teeters on the brink of political chaos, and Eva’s fate is intertwined with guerrilla fighters and revolutionaries, she will find her life’s calling—and the soul mate who will envelop her in a love entirely beyond her mystical inventions.

It has the same issue as Oscar Wao (actually for the same reason, probably): they're not "fantasy" in the sense of world-building and dragons, but "with fantastical and magical elements."

I also used to really like books by Sheri S Tepper, and a few of them had women's rights themes, but I can't remember any PoCs or non-cis main characters off the top of my head. She writes sci fi, but they were enough on the fantasy end of the spectrum that I could handle them. I'm not really a sci fi person.

I also dug up this Amazon list: "Multicultural Speculative Fiction".

Also, I found a "Multicultural Graphic Novels" list which probably isn't for you but looked too awesome to not mention.

Editing to add:

"The Privilege of the Sword": technically Young Adult, I think. The uncle is gay. Or maybe bi. I think he had orgies. Yeah, that would make him bi, I think.

Patricia Briggs: Mercy Thompson. This entire series. The protagonist is half native american, and she works in a garage. The entire series is pretty imaginative, although I can't remember that her heritage is really dealt with other than "and that's why she can turn into a coyote." Patricia Briggs has been one of my favorite writers pretty much since I was a teen. Before she got popular. I'm a hipster.

Another Amazon list: "Some Lesbian Fantasy and SF Favorites". I recognize a lot of the authors' names, but the only one I've read anything by is Tanya Huff. She's very good, and the rest that I recognize have high reviews and good reputations.

Another list along the same lines

Patricia Briggs.