Reddit mentions of Motorcycle Journeys Through The Appalachians - 2nd Edition (Motorcycle Journeys)

I've done similar trips with both car/bike from New England to down there. I'd say skip Skyline Drive. It's nice, but it's really slow and IMO the scenery and riding is waay better on the BRP. If you are going to do the whole BRP, I would suggest planning on two days to do it. You'll want to stop a lot and take pictures and explore little things, plus you have to get off the parkway to get gas/food and that can easily eat up an hour here or there. Blowing Rock, NC is a nice place for a pit stop btw, I recommend the Blowing Rock Ale House. Like another user said, check out the "Back of the Dragon" - great riding. There's actually a TON of great riding all along the BRP. I'd suggest picking up the book "Motorcycle Journeys Through the Appalachians" to give you some ideas:

https://www.amazon.com/Motorcycle-Journeys-Through-Appalachians-2nd/dp/1884313485/ref=sr_1_2?ie=UTF8&qid=1491137415&sr=8-2&keywords=Motorcycle+Journeys+Through+the+Appalachians

Also, that book has a bunch of routes through PA and WV which I imagine you'll have to travel right through from Toronto, so maybe you can incorporate some of them into your trip.

While the BRP is fantastic, and I practically had a religious moment riding the whole thing and being drunk on scenery, the really great riding is to be found just off it and you REALLY need to explore off it if you are coming all the way down. If you are riding the whole thing, Asheville, NC is a fantastic place near the tail end of it - if you like good food and craft beer it should not be missed. Definitely spend a day there if you can.