Reddit mentions of Pathophysiology of Disease: An Introduction to Clinical Medicine 7/E (Lange Medical Books)

The gold standard in emergency medicine is Tintinalli's (https://www.amazon.com/Tintinallis-Emergency-Medicine-Comprehensive-Internal/dp/007179476X/ref=sr_1_1?ie=UTF8&qid=1504698322&sr=8-1&keywords=emergency+medicine+study+guide) although it is a massive book both in size and in depth.

Physiological medicine (https://www.amazon.com/Physiological-Medicine-Clinical-Approach-Physiology/dp/0070381283/ref=sr_1_1?s=books&ie=UTF8&qid=1504698440&sr=1-1&keywords=%22physiological+medicine%22) is amazing.

Pathophysiology of Disease is also good (https://www.amazon.com/Pathophysiology-Disease-Introduction-Clinical-Medicine/dp/0071806008/ref=sr_1_1?s=books&ie=UTF8&qid=1504698512&sr=1-1&keywords=pathophysiology+of+disease).

Costanzo is really what you need.

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It is a pretty easy read, and it gives excellent well-rounded basic science in a fairly easy-to-digest format.

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If you want a second companion book, I would get "Pathophysiology of Disease: An Introduction to Clinical Medicine" published by Lange, authors Gary D. Hammer and Stephen J. Mcphee. It is excellent, high yield for boards, and a great integration.

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I own it, and it's one of the few books I actually used regularly besides Constanzo and Pathoma. The few bad ratings are typically from nurses, which makes sense... this isn't written for nursing students or NPs, it's written for MDs. The extra basic science knowledge we have (are supposed to have, anyways) makes the difference IMO.


Seriously, it's a great buy. The new edition comes out in 2 weeks, not sure if there are any major changes. I have the 7e, which is 56 bucks now vs the 86 for the new edition.

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THis would be an excellent book to develop an Anki deck around IMO.

Lange Pathophysiology of Disease (http://www.amazon.com/Pathophysiology-Disease-Introduction-Clinical-Medicine/dp/0071806008/ref=sr_1_1?s=books&ie=UTF8&qid=1462138694&sr=1-1&keywords=lange+pathophysiology)-- EDIT: Has a good section on diabetes but is also expensive with a ton of additional diseases. I can try to take some pictures of the diabetes section if youd like.

This is a good youtube video on the different classes of medication:
https://www.youtube.com/watch?v=IMLVbEzM0DI

The basics come down to Type I is autoimmune: your body has created antibodies for the beta cells in the pancreas, the cells that produce insulin, which tags the cells for destruction by the immune system.
Type II: Caused by decrease insulin secretion and insulin resistance; meaning that the insulin produced by the pancreas does not stimulate cells to take up glucose. Central adipose tissue (belly fat) promotes the insulin resistance (a number of cytokines and other factors are released, I can give more info if you want). Interestingly, Type II has a stronger genetic component than Type I.

Let me know if you have any other questions. This is really basic but I think gives a good general idea of what is going on.