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You should be able to perfectly do it with that hardware.

I would suggest using an arm board since it will eat <5% energy of that setup, and since you plan 24x7 on, it will add expenses.

Check Pine RockPro64[1], as it has USB-3 and USB-C, gigabit ethernet and you can run it from an eMMC card. Then you can attach an USB storage [2] to it.

Beware: The learning curve can be steep. Also, if you go the USB path make sure the board and the cage support UASP as it will significantly speed the cage access and throughoutput.

[1] https://www.pine64.org/rockpro64/
[2] https://www.amazon.com/ORICO-External-Enclosure-Support-Aluminum/dp/B07XL2BS53

I have that box and actually don't recommend it for the OPs use. Get this one instead
https://www.amazon.com/gp/aw/d/B003X26VV4/ref=psdcmw_160354011_t1_B003YFHEAC

The difference is that this one does not support raid. It might sound like a good idea to have raid running in the box, but in order to do it so you don't risk corrupting your array you need to use NAS rated drives (i.e. wd red drives). If any of your drives aren't you risk corrupting your array and losing all your data. Instead what I'd suggest is to use the box I linked then run snapraid in OMV ( there's a plugin for it). You don't get real time protection, but for most people it should be good enough.

Also look into using a rock64 instead. It has gigabit LAN and usb 3.0 which should make it much faster.

Flash drives and SSD's are almost exactly the same technology. There is really very little difference in the two if you buy a quality flash drive. I use the flash memory plugin on my SSD. I'm not sure it's 100% required since most SSD's support TRIM, but it doesn't hurt anything.

If you don't want to have your flash drive hanging outside the case.. and you have an internal motherboard header.. you can get a cable to plug the flash drive right into the header.... Obviously you would probably lose an external USB port, but it would protect against someone just snatching the flash drive out of your NAS. That is always my chief concern with external flash drives for the OS. To easy for someone to be looking for a flash drive, "find" the one on your server, then when windows can't write to it, formatting it and maybe not even realize what they done (if they aren't tech savvy)

For USB 2.0
https://www.amazon.com/StarTech-Motherboard-4-Pin-Header-USBMBADAPT/dp/B000IV6S9S/ref=mp_s_a_1_3?keywords=usb+flash+drive+header+cable&qid=1564302415&s=gateway&sr=8-3


For USB 3.0 Headers
https://www.amazon.com/Female-Screw-Panel-Mount-Motherboard/dp/B010NBLRHK/ref=mp_s_a_1_14?keywords=usb+flash+drive+header+cable&qid=1564302415&s=gateway&sr=8-14

I used this unit

Mediasonic HFR2-SU3S2 PRORAID 4 Bay 3.5" SATA Hard Drive Enclosure - USB 3.0 & eSATA

https://www.amazon.com/dp/B003YFHEAC/ref=cm_sw_r_cp_api_SV42AbEH8MCAA

I started with an Odroid XU4Q but had to switch to an Intel NUC (Celeron) to host OMV4 since some of the plugins I wanted to use were not available on ARM.

It's in a Dock https://www.amazon.co.uk/gp/aw/d/B00T0ZRAOK/ref=pd_aw_sim_sbs_147_of_13?ie=UTF8&psc=1&refRID=F0MA7G5H7Y5J28C4RT82

I have just built the server as the last one died. This HDD is my backup and I tried to copy to the server but couldn't mount the drive.

It was saying "error something something NTFS something"

So i plugged it into a raspberry pi and transferred the files over the network (which took allot longer than i wanted) and wiped the backup HDD using gparted to ext4.

I have now hooked it up to the server again to back everything up and noticed the serial number is just 000000's

I haven't tried to do anything with it since as i don't want it to mess anything up.

Any advice would be greatly appreciated...