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Not at all. Just make sure that when you clean them use a really mild soap, like a drop of body soap or facial soap, so it doesn't dry out your brushes. And always lube them up before you put them away. If you're gonna be using acrylic then use something like olive oil, but only a drop (trust me it goes a long way) and that shouldn't interfere with the paints too much, just make sure you give it a few wipes with a damp towel before you start painting.

Once you get the enamels, switch to a more resilient lubricant. I use 10w-30 motor oil (clean of course), no joke. It does a great job of keeping those fine hairs from drying out, not to mention its super cheap and always around.

My routine is paint -> clean with spirits -> lube (a drop of oil) -> shape the hairs and work in the oil with your fingers.

One other thing, when you paint, you might notice you get some super tiny lines when you start your lines that are near impossible to meet up with other lines cleanly. There is a trick to trimming the tip of the brush to help with that. If you trim it only take the very very tip off no more than 1/32" - 1/16".

The other trick is to use a shop towel/rag to wipe the strays. You can wipe those strays in tight areas by wrapping the rag/towel around a pointy object like a pencil or the end of a long-handle brush. I use a cuticle pusher that I "borrowed" from my wife....
Like this one: cuticle pusher

Ok, thats a pretty long response. Hope I didn't rack your brain there. Good luck and keep at it. Practice on EVERYTHING. Just about every box, tool, cabinet, etc, is striped in my garage from practicing. Lately, I've been toying with the idea of striping some of my guns. For some reason, a hot-rod looking AR-15 sounds pretty dang cool.

And start simple. It will look better and you'll enjoy it more.

-P