Reddit mentions of Thorne Research - Vitamin K2 Liquid (1 mg/Drop) - Concentrated Vitamin K2 Supplement for Heart and Bone Support - 30 ml

D and fish oil in the morning - Vitamin D has an inverse relationship with melatonin. This means it helps you wake up and increase the melatonin to serotonin shift that happens every morning, peaking around 11am. Fish oils brain health effects would be optimized taking this time of day for related reasons and it's a fat too which helps vitamin D absorption.

Magnesium with lunch - just take it separate from the calcium which it competes with

Calcium with dinner - it's a natural muscle relaxant.

If you're taking Vitamin D you should really consider K2. Vitamin D is actually a pro-hormone and it increases free calcium in the blood stream. This is bad for various reasons. K2 will redirect that calcium from the bloodstream into teeth, bones and way from soft tissue. The K2 and D3 will work with your supplemental calcium in the most optimal way to support bone health.

These are both high quality

https://innovixlabs.com/products/full-spectrum-vitamin-k2/

or

https://www.lifeextension.com/vitamins-supplements/item02335/super-k-elite

Much of the research with K2/Osteoporosis used the MK-4 form at 15milligrams per day. If you want to try that I would suggest Thorne Mk4. I use 5 or 6 drops/day myself. If you do 5 drops this should last almost a year.

https://www.amazon.com/Thorne-Research-Vitamin-Liquid-drop/dp/B000FGWDTK

​

Some information about K2 https://chrismasterjohnphd.com/blog/2016/12/09/the-ultimate-vitamin-k2-resource/

Get Thorne Vitamin K drops - http://www.amazon.com/THORNE-RESEARCH-Vitamin-Liquid-Health/dp/B000FGWDTK

1 bottle is $65, yes, but it will last forever. 1 drop has 1 mg of k2. One bottle has 2700 drops according to the label.

I've been taking it for about a year, no side effects. I also haven't noticed benefits, but that's expected according to the article.

This is the brand of K2 I take. Good high dose.

https://www.amazon.com/Relentless-Improvement-Naturally-Derived-No-Fillers-Science-Based/dp/B00GZVM092

If money is no object, the Thorne drops are considered the best in terms of bioavailability:

https://www.amazon.com/Thorne-Research-Vitamin-Liquid-drop/dp/B000FGWDTK

This is MK4, which is the K2 form that's been studied the most in terms of increasing bone density. MK4 doesn't stay in the blood for very long though - for that, you need MK7. It stays in the blood for much longer, but the studies haven't yet been done to determine whether it's as good as MK4 for building bone density (the reason why I take K2). If your primary need for K2 is for improving sleep, maybe MK7 might be better? I also take MK7 sometimes, the best one I've found is this one:

https://www.amazon.com/absorption-clinically-Formulated-Certified-Veggie-Softgels/dp/B00JGCPAYY

Bear in mind that you need to take K2 with a fat source to maximize availability - taking it without fat is a total waste. The K7 brand above includes coconut oil in the capsule for this reason, but I'm not sure it's enough. I always take K2 with a nice big spoonful of hemp oil.

It's also worth pointing out that K2 MK4 has been shown to increase testosterone levels, which may be a bonus or a deal killer depending on your current levels.

I had the same question in the Vitamin K thread last week. I was show
this and
this.

> You'd need to take a LOT.

A lot is a gross understatement. You'd need to take a lot a lot a lot. 1 cup of cooked kale contains quite a bit more than the RDA.

I use Thorne Research's liquid at 5-15mg a day for years now where the RDA is 120mcg for an adult male which means I'm getting 41-125x the RDA. A lot of people believe the RDA for vitamin k is way way way way way low.

Dosing is an interesting issue when it comes to the K vitamins. For example, the amount considered "adequate" to meet our health needs is very tiny, in the microgram range. Yet in Japan, as you mentioned, doctors often use K2 in the MK4 form to treat osteoporosis, yet when they do that, the amounts are in the milligram range.

To put that into perspective, I believe in Japan they recommend 45 milligrams daily to treat osteoporosis. But the "Adequate Intake" or AI for vitamin K is 90 micrograms for a woman, 120 micrograms for a man. 45 milligrams is 45,000 micrograms. I mean milligrams is still a very small dose but for treatment levels it's still thousands of times more than what science currently considers "adequate."

Here's a side question. What's the largest supplemental dose of any of the K vitamins that you've been able to find? I currently use the Life Extension Super K complex: http://www.lifeextension.com/Vitamins-Supplements/item01834/Super-K-with-Advanced-K2-Complex It has a mix of K2 as both MK7 and MK4, plus it also has K1. I take that twice a day, plus a few hundred micrograms more in other forms.

The largest single dose Vitamin K in any form I've been able to find is Thorne Research in liquid form as K2 in the MK4 form. http://www.amazon.com/Thorne-Research-Vitamin-Liquid-drop/dp/B000FGWDTK

It's expensive at almost $65 a bottle. But cost per unit, it's still very cheap I think. Each drop is 1 milligram of MK4 K2. That's equivalent to 10 pills at 100 micrograms each. If you did a drop a day, the bottle has about 1200 drops so it would last a while. But if you wanted to do what the Japanese do and do 45 milligrams a day, the bottle would last only about 26 days at 45 drops a day. even at the 1 milligram dose, it's still way larger than the 100 microgram pills I've been able to find for K2 MK4.

Most K supplements are in the microgram range. The Life Extensions is the largest single dose I could find.

Have you been able to find any other large dose supplements of any of the K vitamins?

LE has a good product, yeah. I also like Thorne's

It's been awhile since i've researched this, but about two years ago when i was looking for a Vitamin K2 supplement the Thorne Research - Vitamin K2 Liquid (1 mg/drop) - 30 ml product was by far the cheapest per mg. The bottle is expensive though (~$64 USD) but it has 1200 drops at 1mg of menatetrenone (MK4) per drop, so the daily cost (if you take 1 drop, or 1mg of MK4, per day) is only $.05 (5 cents). The Life Extension product that OP linked to for example is 20 cents per day (or 16 cents per mg of mk4+mk7), which is about 4 times more expensive than the Thorne Research product.